Many of Australia's broadacre crops have or will have herbicide tolerance traits added in the future. Cotton, canola, clover and wheat are just a few of the crops that are either being conventionality bred or genetically modified to tolerate both new and old herbicides. Cotton currently has Roundup Ready@ technology with the possibility of other herbicide traits being introduced in the future, however, we need to mindful of the entire farming system and other rotation crops with similar traits being introduced. This is an important period where researchers, regulators, utilisers of the technology and consumers must communicate with each other in a timely manner where and how this technology should be utilised. In the case of cotton there are a large number of potential advantages but an equally large number of management considerations including, herbicide resistance, management of volunteers and herbicide application issues. This presentation attempts to cover some of the important considerations for cotton growers utilising herbicide tolerant cotton