There are several important questions that have been raised about the black root rot pathogen, including: How can one detect black root rot? What makes it spread so fast? What makes it so hard to control? Would rotation with other crops, or fallow, reduce or control the disease? How about biofumigation? Could black root rot episodes be predicted? Are there any means for controlling black root rot? What is next in black root rot research? This review has been written in an attempt to answer some questions on what is known, unknown and currently investigated about cotton black root rot. It is answered from a microbiologist perspective.