Glyphosate is the single most commonly used herbicide applied through shielded sprayers for controlling Post emergent weeds. A number of weeds are becoming tolerant to Glyphosate, forcing farmers to increase rates in order to achieve acceptable commercial control. Using higher rates of Glyphosate increases the risk of crop damage and subsequent yield loss when drift occurs. A number of alternative herbicides were evaluated to determine the potential for their use through shielded sprayers. We evaluated weed efficacy and crop safety for cotton